Hematological Malignancies and Role of Rab7 Protein
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1
Hematological Malignancies and Role of Rab7 Protein
DE NW
ISBN: 9783330006997 bzw. 3330006994, in Deutsch, neu.
Lieferung aus: Vereinigtes Königreich Großbritannien und Nordirland, Lieferzeit: 11 Tage, zzgl. Versandkosten.
Dysregulated growth factor signalling is one of the main causes of the haematological malignancies. Rab 7 plays an important role in the trafficking of growth factor receptors. This study was conducted to see whether knockdown of Rab 7 protein affects growth factor receptor signalling. Inhibition of Rab 7 can enhance phosphorylation of ERK 1/2 induced with IGF being stronger and sustainable, while EGF promotes activation of ERK 1/2 but not as strong as IGF. This means that Rab 7 plays an important and crucial role in the regulation of the growth factor receptor trafficking by maintaining homeostasis of the cell. On the other hand defects or changes in the Rab7 protein by alteration in its gene through internal or external sources, causes derailed growth factor receptor signalling. Rab proteins and associated regulatory factors are frequents targets of mutation and or altered expression in a variety of haematological malignancies. If anything causing change in the Rab 7 either internal or external , responsible for the dysregulated growth factor receptor signalling leading to uncontrolled cell proliferation and ultimately to haematological malignancy.
Dysregulated growth factor signalling is one of the main causes of the haematological malignancies. Rab 7 plays an important role in the trafficking of growth factor receptors. This study was conducted to see whether knockdown of Rab 7 protein affects growth factor receptor signalling. Inhibition of Rab 7 can enhance phosphorylation of ERK 1/2 induced with IGF being stronger and sustainable, while EGF promotes activation of ERK 1/2 but not as strong as IGF. This means that Rab 7 plays an important and crucial role in the regulation of the growth factor receptor trafficking by maintaining homeostasis of the cell. On the other hand defects or changes in the Rab7 protein by alteration in its gene through internal or external sources, causes derailed growth factor receptor signalling. Rab proteins and associated regulatory factors are frequents targets of mutation and or altered expression in a variety of haematological malignancies. If anything causing change in the Rab 7 either internal or external , responsible for the dysregulated growth factor receptor signalling leading to uncontrolled cell proliferation and ultimately to haematological malignancy.
2
Hematological Malignancies and Role of Rab7 Protein
DE PB NW
ISBN: 9783330006997 bzw. 3330006994, in Deutsch, LAP Lambert Academic Publishing, Taschenbuch, neu.
Lieferung aus: Deutschland, Versandkostenfrei.
Hematological Malignancies and Role of Rab7 Protein: Dysregulated growth factor signalling is one of the main causes of the haematological malignancies. Rab 7 plays an important role in the trafficking of growth factor receptors. This study was conducted to see whether knockdown of Rab 7 protein affects growth factor receptor signalling. Inhibition of Rab 7 can enhance phosphorylation of ERK 1/2 induced with IGF being stronger and sustainable, while EGF promotes activation of ERK 1/2 but not as strong as IGF. This means that Rab 7 plays an important and crucial role in the regulation of the growth factor receptor trafficking by maintaining homeostasis of the cell. On the other hand defects or changes in the Rab7 protein by alteration in its gene through internal or external sources, causes derailed growth factor receptor signalling. Rab proteins and associated regulatory factors are frequents targets of mutation and or altered expression in a variety of haematological malignancies. If anything causing change in the Rab 7 either internal or external , responsible for the dysregulated growth factor receptor signalling leading to uncontrolled cell proliferation and ultimately to haematological malignancy. Englisch, Taschenbuch.
Hematological Malignancies and Role of Rab7 Protein: Dysregulated growth factor signalling is one of the main causes of the haematological malignancies. Rab 7 plays an important role in the trafficking of growth factor receptors. This study was conducted to see whether knockdown of Rab 7 protein affects growth factor receptor signalling. Inhibition of Rab 7 can enhance phosphorylation of ERK 1/2 induced with IGF being stronger and sustainable, while EGF promotes activation of ERK 1/2 but not as strong as IGF. This means that Rab 7 plays an important and crucial role in the regulation of the growth factor receptor trafficking by maintaining homeostasis of the cell. On the other hand defects or changes in the Rab7 protein by alteration in its gene through internal or external sources, causes derailed growth factor receptor signalling. Rab proteins and associated regulatory factors are frequents targets of mutation and or altered expression in a variety of haematological malignancies. If anything causing change in the Rab 7 either internal or external , responsible for the dysregulated growth factor receptor signalling leading to uncontrolled cell proliferation and ultimately to haematological malignancy. Englisch, Taschenbuch.
3
Hematological Malignancies and Role of Rab7 Protein (2016)
EN PB NW
ISBN: 9783330006997 bzw. 3330006994, in Englisch, 52 Seiten, LAP LAMBERT Academic Publishing, Taschenbuch, neu.
Lieferung aus: Vereinigte Staaten von Amerika, Usually ships in 24 hours.
Von Händler/Antiquariat, Amazon.com.
Dysregulated growth factor signalling is one of the main causes of the haematological malignancies. Rab 7 plays an important role in the trafficking of growth factor receptors. This study was conducted to see whether knockdown of Rab 7 protein affects growth factor receptor signalling. Inhibition of Rab 7 can enhance phosphorylation of ERK 1/2 induced with IGF being stronger and sustainable, while EGF promotes activation of ERK 1/2 but not as strong as IGF. This means that Rab 7 plays an important and crucial role in the regulation of the growth factor receptor trafficking by maintaining homeostasis of the cell. On the other hand defects or changes in the Rab7 protein by alteration in its gene through internal or external sources, causes derailed growth factor receptor signalling. Rab proteins and associated regulatory factors are frequents targets of mutation and or altered expression in a variety of haematological malignancies. If anything causing change in the Rab 7 either internal or external , responsible for the dysregulated growth factor receptor signalling leading to uncontrolled cell proliferation and ultimately to haematological malignancy. Paperback, Oznaka: LAP LAMBERT Academic Publishing, LAP LAMBERT Academic Publishing, Skupina izdelkov: Book, Objavljeno: 2016-11-11, Datum izdaje: 2016-11-11, Studio: LAP LAMBERT Academic Publishing.
Von Händler/Antiquariat, Amazon.com.
Dysregulated growth factor signalling is one of the main causes of the haematological malignancies. Rab 7 plays an important role in the trafficking of growth factor receptors. This study was conducted to see whether knockdown of Rab 7 protein affects growth factor receptor signalling. Inhibition of Rab 7 can enhance phosphorylation of ERK 1/2 induced with IGF being stronger and sustainable, while EGF promotes activation of ERK 1/2 but not as strong as IGF. This means that Rab 7 plays an important and crucial role in the regulation of the growth factor receptor trafficking by maintaining homeostasis of the cell. On the other hand defects or changes in the Rab7 protein by alteration in its gene through internal or external sources, causes derailed growth factor receptor signalling. Rab proteins and associated regulatory factors are frequents targets of mutation and or altered expression in a variety of haematological malignancies. If anything causing change in the Rab 7 either internal or external , responsible for the dysregulated growth factor receptor signalling leading to uncontrolled cell proliferation and ultimately to haematological malignancy. Paperback, Oznaka: LAP LAMBERT Academic Publishing, LAP LAMBERT Academic Publishing, Skupina izdelkov: Book, Objavljeno: 2016-11-11, Datum izdaje: 2016-11-11, Studio: LAP LAMBERT Academic Publishing.
4
Hematological Malignancies and Role of Rab7 Protein
DE PB NW
ISBN: 3330006994 bzw. 9783330006997, in Deutsch, LAP Lambert Academic Publishing, Taschenbuch, neu.
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
5
Hematological Malignancies and Role of Rab7 Protein
~EN PB NW
ISBN: 3330006994 bzw. 9783330006997, vermutlich in Englisch, LAP Lambert Academic Publishing, Taschenbuch, neu.
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
8
Hematological Malignancies and Role of Rab7 Protein (2016)
DE PB NW
ISBN: 9783330006997 bzw. 3330006994, in Deutsch, Taschenbuch, neu.
Lieferung aus: Deutschland, Next Day, Versandkostenfrei.
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
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