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Expression and Analysis of Recombinant Ion Channels: From Structural Studies to
17 Angebote vergleichen
Preise | 2013 | 2014 | 2015 | 2022 |
---|---|---|---|---|
Schnitt | € 172,19 | € 133,90 | € 168,40 | € 168,55 |
Nachfrage |
Expression and Analysis of Recombinant Ion Channels (2006)
ISBN: 9783527312092 bzw. 3527312099, in Deutsch, Wiley-VCH, gebundenes Buch.
Von Händler/Antiquariat, Ergodebooks.
Wiley-VCH, 2006-03-10. 1. Hardcover. Used:Good. Buy with confidence. Excellent Customer Service & Return policy. Ships Fast. 24*7 Customer Service.
Expression and Analysis of Recombinant Ion Channels
ISBN: 9783527312092 bzw. 3527312099, in Deutsch, Wiley-VCH Verlag GmbH.
Expression and Analysis of Recombinant Ion Channels Clare, Jeffrey J. / Trezise, Derek J. Filling the gap created over the past five years, during which many new techniques have entered the market, this book is directed at both the new and the experienced ion channel researcher wishing to learn more about the considerations and methods for studying recombinant ion channels. These latest developments are covered here for the first time, contributed by editors and authors working for major pharmaceutical companies and who routinely apply these techniques in their daily work. The first three chapters cover the use of the Xenopus oocyte expression system for structure-function studies, from basic approaches for manipulating ion channel cDNAs to more specialized but powerful techniques. This is followed by reviews of strategies and methodologies available for expressing channels in mammalian cells and for their analysis by patch-clamp electrophysiology. Chapters 6 to 8 review the latest methodologies for ion channel drug discovery, including high throughput screening using fluorescence and luminescence, as well as automated planar array electrophysiology. The remaining two chapters focus on approaches for determining ion channel crystal structures and on computational approaches to understanding channel mechanisms at atomic resolution. Rather than provide detailed protocols, indicated by references in each chapter, the authors provide a comprehensive and easily accessible overview of the techniques involved, reviewing underlying principles and providing working guidelines as well as an understanding of the key theoretical and practical considerations associated with each topic. In each case, this practical advice is illustrated by real life examples, taken either from the author's own experience or from key examples in the literature, providing valuable practical hints not found elsewhere. The result is a compendium of practical ion channel information that will prove a valuable resource to academic and industrial workers alike.
Expression and Analysis of Recombinant Ion Channels: From Structural Studies to Pharmacological Screening (2006)
ISBN: 9783527312092 bzw. 3527312099, in Deutsch, Wiley-VCH, gebundenes Buch.
Von Händler/Antiquariat, Ergodebooks.
Wiley-VCH, 2006-04-03. Hardcover. Used:Good. Buy with confidence. Excellent Customer Service & Return policy. Ships Fast. 24*7 Customer Service.
Expression and Analysis of Recombinant Ion Channels
ISBN: 9783527312092 bzw. 3527312099, in Deutsch, Wiley-VCH Verlag GmbH, gebundenes Buch, neu.
Expression and Analysis of Recombinant Ion Channels
ISBN: 9783527312092 bzw. 3527312099, in Englisch, Wiley-VCH, Weinheim, Deutschland, neu.
Filling the gap created over the past five years, during which many new techniques have entered the market, this book is directed at both the new and the experienced ion channel researcher wishing to learn more about the considerations and methods for studying recombinant ion channels. Filling the gap created over the past five years, during which many new techniques have entered the market, this book is directed at both the new and the experienced ion channel researcher wishing to learn more about the considerations and methods for studying recombinant ion channels. These latest developments are covered here for the first time, contributed by editors and authors working for major pharmaceutical companies and who routinely apply these techniques in their daily work. The first three chapters cover the use of the Xenopus oocyte expression system for structure-function studies, from basic approaches for manipulating ion channel cDNAs to more specialized but powerful techniques. This is followed by reviews of strategies and methodologies available for expressing channels in mammalian cells and for their analysis by patch-clamp electrophysiology. Chapters 6 to 8 review the latest methodologies for ion channel drug discovery, including high throughput screening using fluorescence and luminescence, as well as automated planar array electrophysiology. The remaining two chapters focus on approaches for determining ion channel crystal structures and on computational approaches to understanding channel mechanisms at atomic resolution. Rather than provide detailed protocols, indicated by references in each chapter, the authors provide a comprehensive and easily accessible overview of the techniques involved, reviewing underlying principles and providing working guidelines as well as an understanding of the key theoretical and practical considerations associated with each topic. In each case, this practical advice is illustrated by real life examples, taken either from the author's own experience or from key examples in the literature, providing valuable practical hints not found elsewhere. The result is a compendium of practical ion channel information that will prove a valuable resource to academic and industrial workers alike.
Expression and Analysis of Recombinant Ion Channels (2006)
ISBN: 9783527608096 bzw. 3527608095, in Englisch, 302 Seiten, Wiley-VCH, neu, Erstausgabe.
Von Händler/Antiquariat, Amazon.com.
Filling the gap created over the past five years, during which many new techniques have entered the market, this book is directed at both the new and the experienced ion channel researcher wishing to learn more about the considerations and methods for studying recombinant ion channels. These latest developments are covered here for the first time, contributed by editors and authors working for major pharmaceutical companies and who routinely apply these techniques in their daily work. The first three chapters cover the use of the Xenopus oocyte expression system for structure-function studies, from basic approaches for manipulating ion channel cDNAs to more specialized but powerful techniques. This is followed by reviews of strategies and methodologies available for expressing channels in mammalian cells and for their analysis by patch-clamp electrophysiology. Chapters 6 to 8 review the latest methodologies for ion channel drug discovery, including high throughput screening using fluorescence and luminescence, as well as automated planar array electrophysiology. The remaining two chapters focus on approaches for determining ion channel crystal structures and on computational approaches to understanding channel mechanisms at atomic resolution. Rather than provide detailed protocols, indicated by references in each chapter, the authors provide a comprehensive and easily accessible overview of the techniques involved, reviewing underlying principles and providing working guidelines as well as an understanding of the key theoretical and practical considerations associated with each topic. In each case, this practical advice is illustrated by real life examples, taken either from the author's own experience or from key examples in the literature, providing valuable practical hints not found elsewhere. The result is a compendium of practical ion channel information that will prove a valuable resource to academic and industrial workers alike. Printed Access Code, Ausgabe: 1, Label: Wiley-VCH, Wiley-VCH, Produktgruppe: Book, Publiziert: 2006-06-22, Studio: Wiley-VCH.
Expression and Analysis of Recombinant Ion Channels
ISBN: 9783527607938 bzw. 3527607935, in Deutsch, Wiley-VCH, Taschenbuch, neu.
Expression and Analysis of Recombinant Ion Channels
ISBN: 9783527607938 bzw. 3527607935, in Deutsch, Wiley-VCH, Weinheim, Deutschland, neu, E-Book, elektronischer Download.
Expression and Analysis of Recombinant Ion Channels - From Structural Studies to Pharmacological Screening
ISBN: 9783527607938 bzw. 3527607935, in Deutsch, Wiley-VCH, neu, E-Book, elektronischer Download.
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
Expression and Analysis of Recombinant Ion Channels : From Structural Studies to Pharmacological Screening
ISBN: 9783527607938 bzw. 3527607935, in Deutsch, Springer Berlin Heidelberg, neu, E-Book, elektronischer Download.
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen